Day 3 | May 18

MAY 18
Session 6 | Amarcord - I remember
Chairs: Diana Ferraro (Modena) & Luca Battistni (Rome)

09:15-10:00 | Secreted immune checkpoints in tumor immune dysfunction: an opposite lesson for autoimmunity
Vincenzo Barnaba (Sapienza Università di Roma, Italy)

10:00-10:15 | #15 Modulation of pro-inflammatory cytokine release by innate immune cells in pwMS during Ocrelizumab treatment
Silvia D’Orso (Santa Lucia Foundation, Italy)

10:15-10:30 | #33 Effects of Ocrelizumab on NK cell activation in Multiple Sclerosis
Gianmarco Abbadessa (University of Campagnia Luigi Vanvitelli, Italy)
10:30-10:45 | #30 Defining post-translational modifications of deoxycytidine kinase to predict lymphocyte response to caldribine using mass spectrometry
Federico Carlini (DINOGMI, Italy)

10:45-11:00 | #47 Deployment of comprehensive high-parameter cytometry to contrast immune changes in PwMS under DMF, Ocrelizumab, Cladribine
Mario Picozza (Fondazione Santa Lucia, Italy)

11:00-11:15 | #27 Multiple Sclerosis associated EBNA2 variants affect the response to pegylated interferon- therapy
Rosella Mechelli (Università Telematica San Raffaele, Italy)
11:15-11:50 Coffee Break
Session 7 | Psycho
Chairs: Nicole Kerlero de Rosbo (Genoa) & Diego Centonze (Rome)

11:50-12:10 | Introduction Immuno-Psychology/Immuno-Psychiatry Group

12:10-13:00 | Mental health impact of Covid-19 pandemic
Fabrizio Starace (AUSL di Modena, Italy)
13:00-14:30 Lunch Break
Session 8 | La Grande Abbuffata (The Big Feast)
Chairs: Martina Severa (Rome) & Marcello Pinti (Modena)

14:30-15:15 | Immunological self-tolerance: bridging the gap among susceptibility to autoimmunity, infections and cancer
Giuseppe Matarese (Università di Napoli "Federico II", Italy)

15:15-15:30 | #13 Impact of caloric restriction in patients with multiple sclerosis treated with dimethyl fumarate
Alice Verdiani (Fondazione Santa Lucia, Italy)

15:30-15:45 | #44 Calorie restriction as a novel therapeutic tool to modulate immune system function during multiple sclerosis
Clorinda Fusco (Consiglio Nazionale Delle Ricerche IEOS-CNR, Italy)

15:45-16:00 | #10 β3-adrenergic receptor-expressing stromal cells in thymus: the watchmen of thymic function
Maria Cristina Mariani (University of Genoa DINOGMI, Italy)
16:00-16:30 Coffee Break
Session 9 | Quarto Potere - Citizen Kane
Chairs: Sara De Biasi (Modena), Patrizia Sola (Modena), Rosella Mechelli (Rome) & Claudio Procaccini (Naples)

16:30-18:00 | Poster Session
#1 Nanotechnology and neuroinflammation: impact of graphene nanoflakes on Experimental Autoimmune Encephalomyelitis
Roberta Amoriello (University of Florence, Italy)

#2 Interleukin 6 SNP rs1818879 regulates radiological and in-flammatory activity in multiple sclerosis
Antonio Bruno (IRCCS Neuromed, Italy)

#3 The BDNF Val66Met polymorphism modulates inflammation and neurodegeneration in the early phases of multiple sclerosis
Ettore Dolcetti (IRCCS Neuromed, Italy)

#4 Lowering neuroinflammatory indices with light: a new neurorehabilitation protocol for Long COVID Syndrome
Federica Peci (San Celestino Institute, Italy)

#5 Looking for final effectors of regulome alteration in MS: AID-dysregulation LMP1-mediated in MS pathogenesis
Rachele Bigi (Università La Sapienza Roma, Italy)

# 6 Microglial Extracellular Vesicles as Therapeutic Vector for Neuroinflammation
Giulia Marostica (Ospedale San Raffaele Srl, Italy)

#7 PD-L2 identifies a novel subpopulation of neutrophils displaying immunoregulatory features in Multiple Sclerosis
Susanna Manenti (Ospedale San Raffaele Srl, Italy)

#8 Dendritic cells educated through exposure to specialized pro-resolving mediators acquire a tolerogenic phenotype
Giovanni Ferrara (IRCCS Ospedale Policlinico San Martino, Italy)

#9 The Enigma: is AgRP neuropeptide new blood biomarker of brain atrophy?
Tiziana Vigo (Ospedale Policlinico IRCCS San Martino, Italy)

#11 Turning-on AgRP neurons in experimental autoimmune encephalomyelitis: signals and mechanisms
Eleonora Cornacchia (IRCCS Polyclinic Hospital San Martino, Italy)

#12 Anti-NG2 autoantibodies as prognostic biomarker in persons with multiple sclerosis
Marta Bottero (IRCCS Policlinico Ospedale San Martino, Italy)

#16 Specialized pro-resolving mediator RvD1 reduces neuroinflammation in a transgenic rat model of Parkinson’s disease
Marta Tiberi (IRCCS Santa Lucia Foundation, Italy)

#17 Immune profiling of plasmatic Extracellular Vesicles in multiple sclerosis: CD24 a molecule of interest
Flavia Giannessi (Fondazione Santa Luci CERC, Italy)

#18 Possible role of the sympathetic nervous system in the definition of glioblastoma immune microenvironment
Erika Ricci (IRCCS Hospitale San Martino, Italy)

#23 Negative Post VZV-Vaccination Immune Response in three patients with R-R MS: “The Case of VZV-Vaccine”
Maria Teresa Ferrò (Neuroimmunology, Center For Multiple Sclerosis, Cardiocerebrovascular Department, ASST Crema, Italy)

#26 RvD1 modulates maturation of monocyte-derived dendritic cells in Multiple Sclerosis
Federico Fazio (IRCCS Fondazione Santa Lucia, Italy)

#28 Characteristics of patients with an elevated kappa index and absent cerebrospinal fluid IgG oligoclonal bands
Krzysztof Smolik (University Of Modena And Reggio Emilia, Italy)

#31 Computational modelling of the immune response in Multiple Sclerosis
Alessandro Maglione (Università degli Studi di Torino, Italy)

#32 Interleukin-9 and astrocytes: a novel axis regulating neuroinflammation
Elisabetta Volpe (Fondazione Santa Lucia, Italy)

#36 Deciphering Multiple Sclerosis endophenotypes through Mendelian disorders: a network-based approach
Gianmarco Bellucci (Sapienza University of Rome, Italy)

#38 S1P receptor modulators may interfere with astrocyte TrkB signalling during neuroinflammation
Emanuela Colombo (Ospedale San Raffaele, Italy)

#39 MiR-142-3p is a critical modulator of TNF-mediated neuronal toxicity in multiple sclerosis
Sara Balletta (Department Of Systems Medicine, Tor Vergata University, Rome, Italy)

#41 Understanding neuroinflammation by studying immune cell interactions with central nervous system-resident cells
Alessandro Bani (University of Verona, Italy)

#42 Early immune signature correlates to BNT162b2 vaccine-induced protection in healthy individuals and Multiple Sclerosis patients
Daniela Ricci (Istituto Superiore Di Sanità, Italy)

#46 AChR and MuSK antibodies detection in Myasthenia gravis: a comparison of cell-based and radioimmunoprecipitation assays
Pietro Businaro (Università di Pavia / Ist. Mondino, Italy)

#49Atezolizumab-induced Anti-ANNA2/Ri Encephalitis with Status Epilepticus in a Patient with Small-Cell Lung Cancer: expanding the spectrum of CNS immune checkpoint inhibitors ‘toxicity’
Luigi Zuliani (San Bortolo Hospital, Italy)

#50 Phenotyping of T-cells derived from the aneurysm wall in a pediatric case of subarachnoid hemorrhage
Giorgia Moschetti (Istituto Nazionale di Genetica Molecolare "Romeo ed Enrica Invernizzi", Italy)

18:00-19:00 | AINI General Assembly
---> MAY 19